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There are several matches for 'heat shock protein 90'.
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2153 matches
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organism
protein
1)
Caenorhabditis elegans
hsp-90 -
Heat
shock
protein
90
; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target
proteins
involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client
proteins
, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. By stabilizing the receptor-type guanylate cyclase daf-11 or another sig [...]
[a.k.a. C47E8.5, 4I2Z, Q18688,
Heat shock protein 90
]
2)
Homo sapiens
TRAP1 -
Heat
shock
protein
75 kDa, mitochondrial; Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA; Belongs to the
heat
shock
protein
90
family.
[a.k.a. 10131, HSP75, UPI00025A2F3A]
3)
Homo sapiens
FKBP4 - Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; Immunophilin
protein
with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with
heat
-
shock
protein
90
(HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May [...]
[a.k.a. 4LAY, ENSP00000438491, R-HSA-162582]
4)
Homo sapiens
FKBP5 - Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin
protein
with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with
heat
-
shock
protein
90
(HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1.
[a.k.a. ENSP00000441205, 4JFM, NM_001145777.1]
5)
Homo sapiens
HSP90AA1 -
Heat
shock
protein
HSP
90
-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target
proteins
involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client
proteins
, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]
[a.k.a. R-HSA-1643713, R-HSA-196854, ENSP00000216281]
6)
Homo sapiens
HSP90AB1 -
Heat
shock
protein
HSP
90
-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target
proteins
involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client
proteins
, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client
protein
classes via its interact [...]
[a.k.a. R-HSA-69278, ENSG00000096384, P08238]
7)
Homo sapiens
HSP90B1 - Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted
proteins
(By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity). Belongs to the
heat
shock
protein
90
family.
[a.k.a. GRP94, ENST00000421266, HSP90B1-202]
8)
Homo sapiens
AHSA1 - Activator of
90
kDa
heat
shock
protein
ATPase homolog 1; Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co- chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client
proteins
. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client
proteins
.
[a.k.a. ENST00000554156, C14orf3, ENST00000557476.2]
9)
Mus musculus
Fkbp4 - Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; Immunophilin
protein
with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with
heat
-
shock
protein
90
(HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May [...]
[a.k.a. AW208983, Fkbp4-201, R-MMU-8939211]
10)
Mus musculus
Fkbp5 - Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin
protein
with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with
heat
-
shock
protein
90
(HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1.
[a.k.a. CH466606, 14229, ENSMUST00000232939]
11)
Mus musculus
Hsp90ab1 -
Heat
shock
protein
HSP
90
-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target
proteins
involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client
proteins
, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client
protein
classes via its interact [...]
[a.k.a. R-MMU-453274, ENSMUST00000130406.1, Tumor-specific transplantation 84 kDa antigen]
12)
Mus musculus
Hsp90aa1 -
Heat
shock
protein
HSP
90
-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target
proteins
involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client
proteins
, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]
[a.k.a. R-MMU-453274, CCDS26172.1, MGI:96250]
13)
Mus musculus
Hsp90b1 - Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted
proteins
. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD) (By similarity). Has ATPase activity ; Belongs to the
heat
shock
protein
90
family.
[a.k.a. BAE35526.1, R-MMU-6785807, GRP94]
14)
Mus musculus
Ahsa2 - Activator of
90
kDa
heat
shock
protein
ATPase homolog 2; Co-chaperone that stimulates HSP90 ATPase activity. Belongs to the AHA1 family.
[a.k.a. BAE23240.1, Ahsa2-204, UPI00001E6FDC]
15)
Mus musculus
Ahsa1 - Activator of
90
kDa
heat
shock
protein
ATPase homolog 1; Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co- chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client
proteins
(By similarity). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client
proteins
.
[a.k.a. ENSMUST00000222728, NM_146036.1, mmu:217737]
16)
Caenorhabditis elegans
enpl-1 - Endoplasmin homolog; Molecular chaperone that functions in the processing and transport of secreted
proteins
; Belongs to the
heat
shock
protein
90
family.
[a.k.a. T05E11.3a, WBGene00011480, T05E11.3b.4]
17)
Escherichia coli K12
rpoE - RNA polymerase sigma E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic
protein
stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as
heat
shock
and oxidative stress; it controls
protein
processing in the extracytoplasmic compartment. The
90
member regulon consists of the genes necessary for the synthesis and maintenance of both
proteins
and LPS of the outer me [...]
[a.k.a. b2573, AAC75626.1, RpoE]
18)
Acetobacter ghanensis
htpG -
Heat
shock
protein
90
; Molecular chaperone. Has ATPase activity.
[a.k.a. AGA_848, CEF54563.1, A0A0U5FVZ3_9PROT,
heat shock protein 90
,
Heat shock protein 90
, ...]
19)
Acetonema longum
htpG -
Heat
shock
protein
90
; Molecular chaperone. Has ATPase activity.
[a.k.a. EGO61764.1, ALO_21631, F7NQC3_9FIRM,
heat shock protein 90
,
Heat shock protein 90
, ...]
20)
Achlya hypogyna
ACHHYP_10677 -
Heat
shock
protein
90
.
[a.k.a. A0A1V9YKT7, A0A1V9YKT7_9STRA,
Heat shock protein 90
]
2153 matches
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